PROF. PHILIP NORTEY

Profile

Associate Professor Philip Nortey is an experienced research chemist and pharmaceutical scientist with extensive expertise in analytical chemistry and drug development. His research focuses on the development of innovative iron chelators for the treatment of sickle cell disease and thalassaemia, contributing to improved therapeutic options for patients with iron overload complications. He is also involved in the development of innovative reversed-phase HPLC columns to enhance analytical efficiency and separation performance.

Professor Nortey brings many years of experience from the UK National Health Service and major pharmaceutical companies, where he worked as a research chemist and quality control analyst for raw materials, active pharmaceutical ingredients (APIs), antibiotics, and finished pharmaceutical products.

He possesses strong theoretical knowledge and practical expertise in analytical instrumentation, including HPLC, GC, UV/Visible spectroscopy, FT-IR, dissolution testing, Karl Fischer titration, TLC, disintegration, tablet hardness, viscometry, and stability studies. His experience extends to method development and validation, instrument calibration, cleaning validation, LIMS application, out-of-specification investigations, SOP development, and compliance with GLP, GMP, and ICH guidelines.

Basic Information
Name: Prof. Philip Nortey
Designation: Associate Professor
Department: Department of Pharmaceutical Chemistry
Institutional Email: pnortey@central.edu.gh
Office Location: Room SB104, Gadzekpo Block

Academic Qualifications/Education:

  • PhD, Analytical Chemistry, University of London (2000)
  • MSc. Analytical Chemistry, University of East London (1985)
  • BSc. Hons Chemistry, University of London (1981)

Research Interests

  • Quality Control testing of finished drugs, antibiotics and raw materials
  • Quality Control & Stability testing of APIs
  • Drug development
  • Analytical instrumentation, including HPLC
  • Environmental analysis

Publications

  • Kontoghiorghes GJ, Barr J, Nortey P, Sheppard L. Selection of new generation of orally active Alpha-ketohydroxypyridine iron chelators intended for use in the treatment of iron overload. American Journal of Haematology 42: 340–349 (1993).
  • FN. Al-Refaie, AV. Hoffbrand, P. Nortey, B. Wonke, DG. Wickens. Response – Oral iron chelator L1 and Autoimmunity. Blood 81, (1993) p1971–1972.
  • FN. Al-Refaie, B. Wonke, P. Nortey, AV. Hoffbrand. Pharmacokinetics of the oral iron chelator L1 in patients with iron overload. British Journal of Haematology, vol 87, Suppl. 1, 1994.
  • FN. Al-Refaie, LN. Sheppard, P. Nortey, B. Wonke, AV. Hoffbrand. Pharmacokinetics and Pharmacodynamics of the oral iron chelator Deferiprone (L1) in patients with iron overload. Clinical Pharmacology and Therapeutics. British Journal of Haematology (1994).
  • FN. Al-Refaie, LN. Sheppard, P. Nortey, B. Wonke, AV. Hoffbrand. Pharmacokinetics of the oral iron chelator Deferiprone (L1) in patients with iron overload. British Journal of Haematology. (Accepted for publication 10th October 1994).
  • D. Hileti, RJ. Ward, TJ. Peters, FN. Al-Refaie, P. Nortey, AV. Hoffbrand. Pharmacokinetics and tissue distribution of 14C-labelled oral iron chelator 1,2 Dimethyl-3-hydroxypyrid-4-one (L1) in the rat. British Journal of Haematology (1994).

Professional Memberships

  • Royal Society of Chemistry: CChem, MRSC, CSci
  • Royal Society of Arts: FRSA (for encouragement of Arts, Manufactures & commerce)
  • Home Office License for Scientific Procedures on Living Animals.

Courses Taught

  • Organic Pharmaceutical Chemistry I (Theory and practical) (Level 100) (UG)
  • Inorganic and Physical Pharmaceutical Chemistry (Theory and practical) (Level 100) (UG)
  • Organic Pharmaceutical Chemistry II (Theory and practical) (Level 200) (UG)
  • Physical Chemistry (Theory and practical) (Level 200) (UG)
  • Pharmaceutical Analytical Chemistry (Theory and practical) (Level 300) (UG)

Outreach and Engagement

  • UK Qualified and Accredited Methodist Preacher and Assessor.

Additional Roles / Responsibilities

  • Academic advisor, level 100 School of Pharmacy (SOP), Central University (CU)
  • On adhoc Executive Committee for the promotion of senior staff.
  • Former Executive Committee Member of the Central Graduate School
  • School of Pharmacy Departmental and Faculty Board Member

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