Senior Lecturer of Chemistry
Department of Pharmaceutical Sciences
Teaching Interests:
I am an Organic Medicinal Chemist. Currently, I teach mainly medicinal Chemistry courses and their associated practical (laboratory) courses.
Even though my expertise is in organic chemistry, I am interested in the teaching of any level of organic, inorganic and physical chemistry courses in addition to the medicinal or pharmaceutical chemistry.
Research Interests:
My area of expertise is the design and synthesis of compounds with potential applications in medicine, pharmaceutical sciences and biomedical sciences. There are two tenets of my research activity. My major research engagement over the years has been the design and synthesis of compounds with potential applications in medicine and biomedical sciences. This research involves creating a synthetic methodology for the development of newer analogs of antimalarial agents as well as the synthesis and evaluation of new anticancer drugs designed to enhance therapeutic oxidations by disfavoring unproductive and toxic oxidative pathways.
The new area of my research is phytochemistry. For this research, I am in collaboration with Professor K. A. Ohemeng. Central to this research interests is phytochemical screening of biologically active components in medicinal plants and total synthesis of natural products with the aim of developing new synthetic methods and strategies. With regard to this research, my newly established research group in the CU-SOP is currently in the process of establishing a collaboration with other research scientists in the Center for Scientific Research into Plant Medicine, (CSRPM), Mampong Akwapim, Ghana. In concert with this collaborative program, we look to nature to inspire our choice of synthetic targets of natural products.
Currently, I am the research/project advisor for a number of fourth and fifth year Pharm. D. students in the CU-SOP. As part of my research interests, I also wish to harness the research potentials of our students who are creative and interested in drug discovery research so that they will develop the interest in pursuing research-oriented professions in the pharmaceutical sciences space.
In due course, I also intend to collaborate with the Central University School of Engineering to engage in interdisciplinary research projects that will be executed by engineering and pharmacy students. This will involve the development of analytical methods for analyses of environmental samples such as water and soil using ICP-MS.
SELECTED RECENT PEER REVIEWED PUBLICATIONS
- d Nikitina; E.V.; Zubkov, F.I. Rearrangement of 2-azanorbornenes to tetrahydrocyclopenta[c]pyridines under the action of activated alkynes – A short pathway for construction of the altemicidin core. Tetrahedron Letters, 2017, 58, 4384-4387.
Hubin, T. J.; Amoyaw, P. N. –A.; Maples R. D.; Le, J. G.; Archibald, S. J.; Khan, S. I.;
Tekwani, B. L.; Khan, M. O. F. Synthesis and antimalarial activity of metal complexes of
cross-bridged tetraazamacrocyclic ligands. Bioorganic & Medicinal Chemistry. 2014, 22
3239–3244.
Email: pamoyaw@hotmail.com
Email: pamoyawpn@central.edu.gh