Profile
Dr. (Pharm) Patrick Gyan is a Lecturer in the Department of Pharmaceutical Chemistry with expertise in medicinal and pharmaceutical chemistry. His research focuses on antimicrobial drug discovery and the design and synthesis of small molecules, including 1,2,3-triazoles, chalcones, phenylhydrazones, and azo compounds.
He is actively involved in antimicrobial resistance (AMR) research, exploring innovative strategies such as biofilm disruption and efflux pump inhibition to enhance antimicrobial efficacy. Dr. Gyan also applies computational drug design tools, including molecular docking and ADME/Tox prediction, to optimize lead compounds and support rational drug development.
In addition, he has strong interests in analytical methods and quality control of medicines, ensuring safety, efficacy, and regulatory compliance. His work integrates synthetic chemistry, computational modeling, and biological evaluation to advance therapeutic discovery and pharmaceutical innovation.
Basic Information
Name: Dr. (Pharm) Patrick Gyan
Designation: Lecturer
Department: Department of Pharmaceutical Chemistry
Institutional Email: patrickgyan468@gmail.com
Office Location: Room SB302, Gadzepko Block.
Academic Qualifications/Education
- M.Phil., Pharmaceutical Chemistry, Kwame Nkrumah University of Science and Technology, 2024
- Doctor of Pharmacy (PharmD), University of Health and Allied Sciences, 2022
Research Interests
- Medicinal and Pharmaceutical Chemistry
- Antimicrobial Drug Discovery
- Small Molecule Synthesis (1,2,3-triazoles, chalcones, phenylhydrazones, azo compounds)
- Antimicrobial Resistance (AMR) Research
- Computational Drug Design (Molecular Docking & ADME/Tox Prediction)
- Biofilm and Efflux Pump Inhibition Studies
- Analytical and Quality Control of Drugs
Publications
Amengor, C. D., Gyan, P., et al. “Substituted chalcones inhibit biofilm formation and efflux pumps of multidrug resistant Staphylococcus aureus: Antimicrobial, molecular docking, ADME and QSAR studies.” Bioorganic Chemistry, 135, 109077, 2025.
Dzidzor, C., Biniyam, P. D., Brobbey, A. A., et al., & Gyan, P. “N-Substituted Phenylhydrazones Kill the Ring Stage of Plasmodium falciparum.” BioMed Research International, 2024.
Amengor, C. D. K., Gyan, P., et al. “Antimicrobial Activity and In Silico ADME Prediction of Synthesised 8-hydroxyquinoline Azo Compounds.” Journal of Pharmaceutical Research International, 2022.
Attoh, C. N. D., Adu, J., Danquah, C. A., et al., & Gyan, P. “Antimicrobial, Antioxidant, and Anti-inflammatory Evaluation of Azo Compounds Based on β-naphthol, Catechol and Quinol Nucleus.” Journal of Pharmaceutical Research International, 2022.
Dzidzor, C., Biniyam, P. D., Gyan, P., & Kekessie, F. K. “Discovery of Phenylhydrazones as Potential Antimalarials: An Integrated Computational Approach.” Research Square, 2024.
Professional Memberships
- Member, Pharmaceutical Society of Ghana (PSGH)
- Member, Academic Research and Social Pharmacist Association (ARSPA)
- Member, Community Practice Pharmacists Association (CPPA, Ghana)
- Academic and Research Collaborator, Interdisciplinary Drug Discovery Teams
Courses Taught
- Organic Pharmaceutical Chemistry I (Theory and practical) (Level 100) (UG)
- Inorganic and Physical Pharmaceutical Chemistry (Theory and practical) (Level 100) (UG)
- Organic Pharmaceutical Chemistry II (Theory and practical) (Level 200) (UG)
- Physical Chemistry (Theory and practical) (Level 200) (UG)
- Pharmaceutical Analytical Chemistry (Theory and practical) (Level 300) (UG)
- Medicinal Chemistry I (Theory and practical) (Level 300) (UG)
- Medicinal Chemistry II (Level 400) (UG)
Outreach and Engagement
- Undergraduate research supervision and project co-supervision
- Laboratory training and mentorship in medicinal chemistry techniques
- Collaborative antimicrobial resistance research initiatives in Ghana